Extract executables by typing "tar xvf gismo_v2.0.tar" Linux ('gismo') and Mac ('gismo.mac') versions are in the 'gismo_v2.0' directory. The executable 'gismo' was compiled under a RedHat 5.9 Linux operating system (kernelrelease 2.6.18-371.1.2.el5) running on an Intel Xeon x86_64 machine. Type ./gismo for usage. Extract CDD benchmark sets by typing "uncompress cdd_test_sets.tar.Z; tar xvf cdd_test_sets.tar" The 'cdd_test_sets' directory contains CDD 'gold standard' alignments in fasta (cd00000.fasta) format. It also contains the corresponding sequence sets (cd00000_gld.seq files). For further information contact: Andrew F. Neuwald Institute for Genome Sciences and Department of Biochemistry & Molecular Biology University of Maryland School of Medicine 801 West Baltimore St. BioPark II, Room 617 Baltimore, MD 21201 Tel: 410-706-6724; Fax: 410-706-1482; E-mail: aneuwald@som.umaryland.edu Home page: http://www.igs.umaryland.edu/~aneuwald